GELIFICATION – A NOVEL, EFFICIENT AND CONVENIENT MATRIX FOR MOLECULAR BIOLOGY REAGENTS

Gelification is a process where components of enzymatic reactions are stabilised at room temperature by the addition of different stabilising agents. This process does not alter protein structures, while interactions between reagents are avoided until the user activates the reaction. Gelification is neither a heat dessication, nor a lyophilisation, and is not based on amorphous matrixes such as agarose. It is a revolutionary chemical-physical process done at room temperature, which makes it so far economically the most cost competitive alternative for stabilisation molecular biology reagents.

The technology has been shown to function perfectly with fluorescent dyes typically used for Real Time DNA amplification, providing therefore an important support in stabilising highly complex and thermolabil reaction mixtures, facilitating in this way automation of diagnostic procedures, as well as allowing the development of easy to use systems. Other advantages encountered by the use of this technology, is the reduction of handling steps, significant time and cost savings, and most important for diagnostics, reduction to a minimum of cross-contaminations.

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